グローバル教養科目（Medicinal Chemistry: From Drug Discovery to Market）

Medicinal Chemistry: From Drug Discovery to Market

The discovery and development of efficacious drugs continue to be a challenging endeavor, requiring constant innovation at every stage. Of a greater challenge is the quest to develop personalized medicines. In this course, students will understand and appreciate the multidisciplinary skill set that is essential for today’s medicinal chemists. Topics covered include structural representation of molecules, structure-activity relationships, pharmacokinetics, pharmacodynamics, drug solubilization as well as economic and legal aspects of launching a drug.

MIMA Search

授業計画

The topics that will be covered include: Medicinal Chemistry Strategies for Discovering Lead Compounds Exploration of Structure Activity Relationships Qualitative Aspects of Structure Activity Relationships Spatial Organization, Receptor Mapping and Molecular Modeling Biotransformation Reactions Drug Transport Mechanisms Pharmacokinetic Properties Formulation Drug Nomenclature Internet and Patents in Medicinal Chemistry

授業の方法

Lectures, class discussions, group-work

成績評価方法

【Please note that this course uses a five-point grading scale of A+, A, B, C, or F(Fail).】 Assessed assignments, pop quizzes, and examinations

教科書

Will be mentioned in class

参考書

Will be mentioned in class

履修上の注意

【If the number of students enrolling in this course exceeds 20, there may be a selection process. Instructions for the selection process will be given in the first class, so if you are interested in taking this course, please be sure to attend the first class.】 (1}The course will be conducted entirely in English. Although not essential, a background in general and organic chemistry will be helpful. (2) Up to 20 students will be, in principle, allowed to register for this class. (3) If more than 20 students come to the first class, instructors make a selection. For details, please follow their guidance.